Bone Cancer Research

US Patent 8772541, Jul 8, 2014 - Cannabinoid receptor 2 (CB2) inverse agonists and therapeutic potential for multiple myeloma and osteoporosis bone diseases

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Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells

Mimeault, Murielle, et al.

Journal of Cellular and Molecular Medicine. 2013, 17(1): 30-54 (Full).

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The Cannabinoid Receptor Type 1 Is Essential for Mesenchymal Stem Cell Survival and Differentiation: Implications for Bone Health

Gowran, Aoife, et al.

Stem Cells International. 2013, e796715 (Full online article).

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Dynamic changes to the endocannabinoid system in models of chronic pain

Sagar, Devi Rani, et al.

Philosophical Transactions of the Royal Society Biological Sciences.  2012 Oct 29, 367: 3300-3311 (Full).

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Cannabinoid Receptor 1 Mediates Glucocorticoid-Induced Bone Loss in Rats by Perturbing Bone Mineral Acquisition and Marrow Adipogenesis

Ko, Jih-Yang, et al.

Arthritis & Rheumatism. 2012 Apr, 64(4): 1204-1214 (Full).

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The putative cannabinoid receptor GPR55 promotes cancer cell proliferation

Hu, G, et al.

Oncogene. 2011, 30: 139-141 (abstract).

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Intrathecal Administration of the Cannabinoid 2 Receptor Agonist JWH015 Can Attenuate Cancer Pain and Decrease mRNA Expression of the 2B Subunit of N-Methyl-D-Aspartic Acid

XiaoPing, Gu, et al.

Anesthesia & Analgesia. 2011 Aug, 113(2): 405-411 (Full).

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Antinociceptive effect of intrathecal cannabinoid receptor agonist WIN 55,212-2 in  a rat bone tumor pain model

Hua Cui, Jin, et al.

Neuroscience Letters. 2011 Apr 15, 493(3): 67-71 (abstract).

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Spinal and peripheral analgesic effects of the CB2 cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain

Curto-Reyes, V, et al.

British Journal of Pharmacology. 2010, 160: 561-573 (Full).

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Cannabinoids and Bone: Friend or Foe?

Idris, Aymen, et al.

Calcified Tissue International. 2010 Oct, 87(4): 285-297 (abstract).

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Reduction of bone cancer pain by the CB1 activation and TPV1 inhibition

Kawamata, Tomoyuki, et al.

Journal of Anesthesia. 2010 Apr 7, 24(2): 328-332 (abstract).

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Professional Perspectives On Addiction Medicine Volume 2

Stanford, Mark, et al.

Beyond Medical Marijuana: Toward Cannabinoid-Based Medicines. 2009, (Full online eBook).

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Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoids

Pereira, Joao P, et al.

Nature Immunology. 2009, 10: 403-411 (abstract).

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Role of type 2 cannabinoid receptor in bone metabolism

Sophocleous, Antonia, et al.

Edinburgh Research Archive. 2009 Nov 25, 1842/5940 (Full online article).

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Reduction of Bone Cancer Pain by Activation of Spinal Cannabinoid receptror 1 and Its Expression in the Superficial Dorsal Horn of the Spinal Cord in a Murine Model of Bone Cancer Pain

Shingo, Furuse, et al.

Anesthesiology. 2009 Jul, 111(1): 173-186 (Full).

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Regulation of Bone Mass, Osteoclast Function, and Ovariectomy-Induced Bone Loss by the Type 2 Cannabinoid Receptor

Idris, Aymen I, et al.

Endocrinology. 2008, 149(11): 5619-5626 (Full).

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Cannabinoid receptors and the regulation of bone mass

Bab, I, et al.
British Journal of Pharmacology. 2008, 153: 182-188 (Full).

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A Decrease in Anandamide Signaling Contributes to the Maintenance of Cutaneous Mechanical Hyperalgesia in a Model of Bone Cancer Pain

Khasabova, Iryna, et al.

Neurobiology of Disease. 2008 Oct 29, 28(44): 11141-11152 (Full).

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Cannabinoids Stimulate Fibroblastic Colony Formation by Bone Marrow Cells Indirectly via CB2 Receptors

Scutt, A, et al.

Calcified Tissue International. 2007 Jan, 80(1): 50-59 (abstract).

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Cannabinoid CB2-Selective Inverse Agonist Protects Against Antigen-Induced Bone Loss

Lunn, Charles A, et al.

Immunopharmacology and Immunotoxicology. 2007, 29(3-4): 387-401 (abstract).