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Bone Cancer Research

US Patent 8772541, Jul 8, 2014 - Cannabinoid receptor 2 (CB2) inverse agonists and therapeutic potential for multiple myeloma and osteoporosis bone diseases

Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells

Mimeault, Murielle, et al.

Journal of Cellular and Molecular Medicine. 2013, 17(1): 30-54 (Full).

The Cannabinoid Receptor Type 1 Is Essential for Mesenchymal Stem Cell Survival and Differentiation: Implications for Bone Health

Gowran, Aoife, et al.

Stem Cells International. 2013, e796715 (Full online article).

Dynamic changes to the endocannabinoid system in models of chronic pain

Sagar, Devi Rani, et al.

Philosophical Transactions of the Royal Society Biological Sciences.  2012 Oct 29, 367: 3300-3311 (Full).

Cannabinoid Receptor 1 Mediates Glucocorticoid-Induced Bone Loss in Rats by Perturbing Bone Mineral Acquisition and Marrow Adipogenesis

Ko, Jih-Yang, et al.

Arthritis & Rheumatism. 2012 Apr, 64(4): 1204-1214 (Full).

The putative cannabinoid receptor GPR55 promotes cancer cell proliferation

Hu, G, et al.

Oncogene. 2011, 30: 139-141 (abstract).

Intrathecal Administration of the Cannabinoid 2 Receptor Agonist JWH015 Can Attenuate Cancer Pain and Decrease mRNA Expression of the 2B Subunit of N-Methyl-D-Aspartic Acid

XiaoPing, Gu, et al.

Anesthesia & Analgesia. 2011 Aug, 113(2): 405-411 (Full).

Antinociceptive effect of intrathecal cannabinoid receptor agonist WIN 55,212-2 in  a rat bone tumor pain model

Hua Cui, Jin, et al.

Neuroscience Letters. 2011 Apr 15, 493(3): 67-71 (abstract).

Spinal and peripheral analgesic effects of the CB2 cannabinoid receptor agonist AM1241 in two models of bone cancer-induced pain

Curto-Reyes, V, et al.

British Journal of Pharmacology. 2010, 160: 561-573 (Full).

Cannabinoids and Bone: Friend or Foe?

Idris, Aymen, et al.

Calcified Tissue International. 2010 Oct, 87(4): 285-297 (abstract).

Reduction of bone cancer pain by the CB1 activation and TPV1 inhibition

Kawamata, Tomoyuki, et al.

Journal of Anesthesia. 2010 Apr 7, 24(2): 328-332 (abstract).

Professional Perspectives On Addiction Medicine Volume 2

Stanford, Mark, et al.

Beyond Medical Marijuana: Toward Cannabinoid-Based Medicines. 2009, (Full online eBook).

Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoids

Pereira, Joao P, et al.

Nature Immunology. 2009, 10: 403-411 (abstract).

Role of type 2 cannabinoid receptor in bone metabolism

Sophocleous, Antonia, et al.

Edinburgh Research Archive. 2009 Nov 25, 1842/5940 (Full online article).

Reduction of Bone Cancer Pain by Activation of Spinal Cannabinoid receptror 1 and Its Expression in the Superficial Dorsal Horn of the Spinal Cord in a Murine Model of Bone Cancer Pain

Shingo, Furuse, et al.

Anesthesiology. 2009 Jul, 111(1): 173-186 (Full).

Regulation of Bone Mass, Osteoclast Function, and Ovariectomy-Induced Bone Loss by the Type 2 Cannabinoid Receptor

Idris, Aymen I, et al.

Endocrinology. 2008, 149(11): 5619-5626 (Full).

Cannabinoid receptors and the regulation of bone mass

Bab, I, et al.
British Journal of Pharmacology. 2008, 153: 182-188 (Full).

A Decrease in Anandamide Signaling Contributes to the Maintenance of Cutaneous Mechanical Hyperalgesia in a Model of Bone Cancer Pain

Khasabova, Iryna, et al.

Neurobiology of Disease. 2008 Oct 29, 28(44): 11141-11152 (Full).

Cannabinoids Stimulate Fibroblastic Colony Formation by Bone Marrow Cells Indirectly via CB2 Receptors

Scutt, A, et al.

Calcified Tissue International. 2007 Jan, 80(1): 50-59 (abstract).

Cannabinoid CB2-Selective Inverse Agonist Protects Against Antigen-Induced Bone Loss

Lunn, Charles A, et al.

Immunopharmacology and Immunotoxicology. 2007, 29(3-4): 387-401 (abstract).

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