top of page

Clinical Endocannabinoid Deficiency (CED) Research

hyperlink to scholar search of CED - 18K+ results

Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes

Russo, E.B.

Cannabis and Cannabinoid Research. 2016, 1(1): 154-165 (full).

Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity

Schlabritz-Loutsevitch, Natalia, et al.

Medical Hypotheses. 2016 Nov, 96: 35-38 (abstract).

Beyond Cannabis: Plants and the Endocannabinoid System

Russo, E.B.

Trends in Pharmacological Sciences. 2016 Jul, 37(7): 594-605 (abstract).

Expression of the Endocannabinoid Receptors in Human Fascial Tissue

Fede, C, et al.

European Journal of Histochemistry. 2016, 60:2643: 130-134 (full).

Anxiety, Stress, and Fear Response in Mice With Reduced Endocannabinoid Levels

Jenniches, Imke, et al.

Biological Psychiatry: A Journal of Psychiatric Neuroscience and Therapeutics. 2016 May, 79(10): 858-868 (abstract).

Endocannabinoids in Multiple Sclerosis and Amyotrophic Lateral Sclerosis 

Pryce, Gareth, et al.

Endocannabinoids, Handbook of Experimental Pharmacology. 2015, 231: 213-231 (abstract). 

Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerol

Kishimoto, Yusushi, et al.

Frontiers in Behavioral Sciences. 2015 Jun 2, 9(134): 1-14 (full).

An Introduction to the Endocannabinoid System: A description of the lipid signaling system essential to health, healing, and homeostasis, long excluded from the medical school curriculum

Sulak, Dustin D.O.

O’Shaughnessy’s. 2015/16 Winter Issue: 3-7 (full).

Are cannabidiol and Δ9-tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review

McPartland, John M., et al.

British Journal of Pharmacology. 2015, 172: 737-753 (full).

Genetic Disruption of 2-Arachidonoylglycerol Synthesis Reveals a Key Role for Endocannabinoid Signaling in Anxiety Modulation

Shonesy, Brian C, et al.

Cell Reports. 2014 Dec 11, 9: 1644-1653 (full).

Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation

Bluett, RJ, et al.

Translational Psychiatry. 2014 Jul 8, 4(e408) (full).

Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System

McPartland, John M., et al.

PlosOne. 2014 Mar 12, online article (full).

Modulating the endocannabinoid system in human health and disease - successes and failures

Pacher, Pal, et al.

The FEBS Journal. 2013 Mar, 280: 1918-1943 (full).  

Effect of Cannabinoid Receptor Activation on Spreading Depression

Kazemi, Hadi, et al.

Iranian Journal of Basic Medical Sciences. 2012 Jul, 15(4): 926-936 (full).

CB1 receptor-deficient mice as a model for depression

Valverde, O., et al.

Neuroscience. 2012 Mar 1, 204: 193-206 (abstract).

Effects of anandamide in migraine: data from an animal model

Greco, Rosaria, et al.

The Journal of Headache and Pain. 2011 Apr, 12(2): 177-183 (abstract).

Endocannabinoid system dysfunction in mood and related disorders

Ashton, C.H., et al.

Acta Psychiatrica Scandinavica. 2011 Oct, 124(4): 250-261 (abstract).

Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress

Wang, Wei, et al.

Neuropsychopharmacology. 2010, 35: 2249-2261 (full).

Review on clinical studies with cannabis and cannabinoids 2005-2009

Hazekamp, Arno, et al.

Cannabinoids. 2010, 5(special issue): 1-21 (full).

The endocannabinoid system and migraine

Greco, Rosaria, et al.

Experimental Neurology. 2010 Jul, 224(1): 95-91 (abstract).

Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment resistant conditions?

Russo, E.B.

Neuro Endocrinology Letters. 2008 Apr 1, 29(2): 192-200 (abstract).

Endocannabinoids in Chronic Migraine: CSF Findings Suggest a System Failure

Sarchielli, Paola, et al.

Neuropsychopharmacology. 2007, 32: 1384-1390 (full).

A possible role for the endocannabinoid system in the neurobiology of depression

Serra, Gino, et al.

Clinical Practice and Epidemiology in Mental Health. 2007 Nov 19, 3:25: 1-11 (full).

The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract

Massa, Federico, et al.

Journal of Molecular Medicine. 2005 Dec, 83(12): 944-954 (abstract). 

Agonistic Properties of Cannabidiol at 5-HT1a Receptors

Russo, E.B., et al.

Neurochemical Research. 2005 Aug, 30(8): 1037-1043 (abstract).

Therapeutic opportunities through modulation of the endocannabinoid system

Makriyannis, Alexandros, et al.

Neuropharmacology. 2005, 48: 1068-1071 (full).

On-demand activation of the endocannabinoid system in the control of neuronal excitability and epileptiform sezures

Lutz, Beat.

Biochemical Pharmacology. 2004 Nov 1, 68(9): 1691-1698 (abstract).

Clinical Endocannabinoid Deficiency: About Us
bottom of page