Clinical Endocannabinoid Deficiency (CED) Research

hyperlink to scholar search of CED - 18K+ results

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Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes

Russo, E.B.

Cannabis and Cannabinoid Research. 2016, 1(1): 154-165 (full).

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Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity

Schlabritz-Loutsevitch, Natalia, et al.

Medical Hypotheses. 2016 Nov, 96: 35-38 (abstract).

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Beyond Cannabis: Plants and the Endocannabinoid System

Russo, E.B.

Trends in Pharmacological Sciences. 2016 Jul, 37(7): 594-605 (abstract).

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Expression of the Endocannabinoid Receptors in Human Fascial Tissue

Fede, C, et al.

European Journal of Histochemistry. 2016, 60:2643: 130-134 (full).

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Anxiety, Stress, and Fear Response in Mice With Reduced Endocannabinoid Levels

Jenniches, Imke, et al.

Biological Psychiatry: A Journal of Psychiatric Neuroscience and Therapeutics. 2016 May, 79(10): 858-868 (abstract).

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Endocannabinoids in Multiple Sclerosis and Amyotrophic Lateral Sclerosis 

Pryce, Gareth, et al.

Endocannabinoids, Handbook of Experimental Pharmacology. 2015, 231: 213-231 (abstract). 

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Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerol

Kishimoto, Yusushi, et al.

Frontiers in Behavioral Sciences. 2015 Jun 2, 9(134): 1-14 (full).

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An Introduction to the Endocannabinoid System: A description of the lipid signaling system essential to health, healing, and homeostasis, long excluded from the medical school curriculum

Sulak, Dustin D.O.

O’Shaughnessy’s. 2015/16 Winter Issue: 3-7 (full).

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Are cannabidiol and Δ9-tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review

McPartland, John M., et al.

British Journal of Pharmacology. 2015, 172: 737-753 (full).

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Genetic Disruption of 2-Arachidonoylglycerol Synthesis Reveals a Key Role for Endocannabinoid Signaling in Anxiety Modulation

Shonesy, Brian C, et al.

Cell Reports. 2014 Dec 11, 9: 1644-1653 (full).

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Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation

Bluett, RJ, et al.

Translational Psychiatry. 2014 Jul 8, 4(e408) (full).

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Care and Feeding of the Endocannabinoid System: A Systematic Review of Potential Clinical Interventions that Upregulate the Endocannabinoid System

McPartland, John M., et al.

PlosOne. 2014 Mar 12, online article (full).

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Modulating the endocannabinoid system in human health and disease - successes and failures

Pacher, Pal, et al.

The FEBS Journal. 2013 Mar, 280: 1918-1943 (full).  

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Effect of Cannabinoid Receptor Activation on Spreading Depression

Kazemi, Hadi, et al.

Iranian Journal of Basic Medical Sciences. 2012 Jul, 15(4): 926-936 (full).

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CB1 receptor-deficient mice as a model for depression

Valverde, O., et al.

Neuroscience. 2012 Mar 1, 204: 193-206 (abstract).

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Effects of anandamide in migraine: data from an animal model

Greco, Rosaria, et al.

The Journal of Headache and Pain. 2011 Apr, 12(2): 177-183 (abstract).

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Endocannabinoid system dysfunction in mood and related disorders

Ashton, C.H., et al.

Acta Psychiatrica Scandinavica. 2011 Oct, 124(4): 250-261 (abstract).

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Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress

Wang, Wei, et al.

Neuropsychopharmacology. 2010, 35: 2249-2261 (full).

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Review on clinical studies with cannabis and cannabinoids 2005-2009

Hazekamp, Arno, et al.

Cannabinoids. 2010, 5(special issue): 1-21 (full).

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The endocannabinoid system and migraine

Greco, Rosaria, et al.

Experimental Neurology. 2010 Jul, 224(1): 95-91 (abstract).

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Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment resistant conditions?

Russo, E.B.

Neuro Endocrinology Letters. 2008 Apr 1, 29(2): 192-200 (abstract).

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Endocannabinoids in Chronic Migraine: CSF Findings Suggest a System Failure

Sarchielli, Paola, et al.

Neuropsychopharmacology. 2007, 32: 1384-1390 (full).

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A possible role for the endocannabinoid system in the neurobiology of depression

Serra, Gino, et al.

Clinical Practice and Epidemiology in Mental Health. 2007 Nov 19, 3:25: 1-11 (full).

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The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract

Massa, Federico, et al.

Journal of Molecular Medicine. 2005 Dec, 83(12): 944-954 (abstract). 

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Agonistic Properties of Cannabidiol at 5-HT1a Receptors

Russo, E.B., et al.

Neurochemical Research. 2005 Aug, 30(8): 1037-1043 (abstract).

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Therapeutic opportunities through modulation of the endocannabinoid system

Makriyannis, Alexandros, et al.

Neuropharmacology. 2005, 48: 1068-1071 (full).

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On-demand activation of the endocannabinoid system in the control of neuronal excitability and epileptiform sezures

Lutz, Beat.

Biochemical Pharmacology. 2004 Nov 1, 68(9): 1691-1698 (abstract).