Alzheimer's Disease 

US Patent 8673368, Mar 18, 2014 - Cannabinoid-containing plant extracts as neuroprotective agents

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US Patent Filing US 6,630,507 B1 Cannabinoids as Antioxidants and Neuroprotectants

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How Cannabinoids May Slow Brain Aging 

Szalavitz, Maia

Time. 2012 Oct 29, (Full News article).

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Cannabinoid Modulation of Neuroinflammatory Disorders

Saito, Viviane M., et al.

Current Neuropharmacology. 2012 Jun, 10(2): 159-166 (Full).

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Terpenoids as Potential Anti-Alzheimer’s Disease Therapeutics

Yoo, Ki-Yeol, et al.

Molecules. 2012 Mar 12, 17(3): 3524-3528 (Full).  

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An Introduction to the Medical Benefits of Cannabis

Acton, Jeremy, et al.

NORML. 2011 Apr 4 (Full).  

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Alzheimer’s disease; taking the edge off with cannabinoids?

Campbell, VA, et al.

British Journal of Pharmacology. 2009 Jan 29, 152(5): 655-662 (Full).

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Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action

Zuardi, Antonio Waldo

Revista Brasileira de Psiquiatria. 2008 Sep, 30(3) (Full). 

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A Molecular Link Between the Active Component of Marijuana and Alzheimer’s Disease Patholiogy

Eubanks, Lisa M., et al.

Molecular pharmaceutics. 2006, 3(6): 773-777 (Full).

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Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

Ehrhart, Jared, et al.

Journal of Neuroinflammation. 2005 Dec 12, 2(29) (Full).

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Prevention of Alzheimer’s Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation

Ramirez, Belen G, et al.

The Journal of Neuroscience. 2005 Feb 23, 25(8): 1904-1913 (Full). 

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Neuroprotective effect of cannabidiol, a non-psychoactive component from cannabis sativa, on β-amyloid-induced toxicity in PC12 cells

Iuvone, Teresa, et al.

Journal of Neurochemistry. 2004 Apr, 89(1): 134-141 (Full).

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Cannabinoids ablate release of TNFα in rat microglial cells stimulated with lypopolysaccharide 

Facchinetti, Fabrizio, et al.

GLIA. 2003 Jan 15, 41(2): 161-168 (Full).

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The therapeutic potential of the endocannabinoid system for Alzheimer’s disease

Karl, Tim, et al.

Expert Opinion on Therapeutic Targets. 2012 Apr, (abstract).

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Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer’s Disease   

Martin-Moreno, Ana Maria, et al.

Molecular Pharmacology. 2011 Feb 24, (abstract).

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Cannabinoid Receptors and Endocannabinoids: Role in Neuroinflammatory and Neurodegenerative Disorders

Bisogno, Tiziana, et al.

CNS and Neurological Disorders: Drug Targets. 2010 Nov, 9(5): 564-573 (abstract). 

Cannabinoid System in Neurodegeneration: New Perspectives in Alzheimer’s Disease

Campillo, N.E., et al.

Mini Reviews in Medicinal Chemistry. 2009 May, (abstract).

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The Role of the Endocannabinoid System in Alzheimer’s Disease: Facts and Hypothesis

Bosogno, Tiziana, et al.

Current Pharmaceutical Design. 2008 Aug, (abstract).

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Cannabinoid CB2 receptor: a new target for controlling neural cell survival?

Fernandez-Ruiz, Javier, et al.

Trends in Pharmacological Sciences. 2007 Jan, (abstract).

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A Molecular Link Between the Active Component of Marijuana and Alzheimer’s Disease Pathology

Eubanks, Lisa M, et al.

Molecular Pharmaceutics. 2006 Aug 9, 3(6): 773-777 (abstract).

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Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in  β-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kB involvement

Esposito, Giuseppe, et al.

Neuroscience Letters. 2006 May 15, 399(1-2): 91-95 (abstract).

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The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt/β-catenin pathway rescue in PC12 cells

Esposito, Giuseppe, et al.

Journal of Molecular Medicine. 2006 Mar, (abstract). 

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The therapeutic potential of cannabis

Baker, David, et al.

The Lancet Neurology. 2003 May, (abstract).

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Amnesia induced by β-amyloid fragments is counteracted by cannabinoid CB1 receptor blockade

Mazzola, Carmen, et al.

European Journal of Pharmacology. 2003 Sep 23, (abstract).