Colon & Colorectal Cancer

US Patent Application 20130059018 A1, Mar 7, 2013 - Phytocannabinoids in the treatment of cancer

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Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer

Aviello, Gabriella, et al.

Journal of Molecular Medicine. 2012 Aug, 90(8): 925-934 (abstract).

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Induction of Apoptosis by Cannabinoids in Prostate and Colon Cancer Cells Is Phosphatase Dependent

Sreevalsan, Sandeep, et al.

Anticancer Research. 2011, 31: 3799-3808 (Full).

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High Tumour Cannabinoid CB1 Receptor Immunoreactivity Negatively Impacts Disease-Specific Survival in State II Microsatellite Stable Colorectal Cancer

Gustafsson, Sofia B, et al.

PLOS ONE. 2011 Aug 25, e0023003 (Full online article).

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Concerted Action of CB1 Cannabinoid Receptor and Deleted in Colorectal Cancer in Axon Guidance

Argaw, Anteneh, et al.

The Journal of Neuroscience. 2011 Jan 26, 31(4): 1489-1499 (Full).

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Effects of Anandamide on Polyamine Levels and Cell Growth in Human Colon Cancer Cells

Linsalata, Michele, et al.

Anticancer Research. 2010, 30: 2583-2590 (Full).

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Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependant NSAID-activated gene-1 in colon cancer cells

Thapa, Dinesh, et al.

Biochemical Pharmacology. 2010 Jul 1, 80(1): 62-71 (abstract).

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The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells

Greenhough, Pastos, et al.

International Journal of Oncology. 2010 Jul, 37(1): 187-193 (abstract).

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Rimonobant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon

Santoro, Antonietta, et al.
International Journal of Cancer. 2009, 125: 996-1003 (Full).

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Cannabinoid Receptor Activation Induces Apoptosis through Tumor Necrosis Factor α-Mediated Ceramide De Novo Synthesis in Colon Cancer Cells

Cianchi, Fabio, et al.

Clinical Cancer Research. 2008, 14: 7691-7700 (Full).

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Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines

Notarnicola, Maria, et al.

Scandinavian Journal of Gastroenterology. 2008, 43(1): 66-72 (abstract).

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The cannabinoid Δ9-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells

Greenhough, Alexander, et al.

International Journal of Cancer. 2007, 121: 2172-2180 (Full).

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A Cannabinoid Anticancer Quinon, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo Study

Kogan, Natalya M, et al.

The Journal of Pharmacology and Experimental Therapeutics. 2007, 322(2): 646-653 (Full)

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The cannabinoid CB2 receptor: a good friend in the gut

Izzo, AA, et al.

Neurogastroenterology & Motility. 2007, 19: 704-708 (Full).

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Involvement of cannabinoid receptors in inflammatory hypersensitivity to colonic distension in rats

Sanson, M, et al.

Neurogastroenterology & Motility. 2006, 18: 949-956 (Full).

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Cannabinoids and cancer: potential for colorectal cancer therapy

Patsos, HA, et al.

Biochemical Society Transactions. 2005, 33(4): 712-714 (Full).

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The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2

Pastos, HA, et al.

GUT. 2005, 54: 1741-1750 (Full).

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Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing

Wright, Karen, et al.

Gastroenterology. 2005 Aug, 129(2): 437-453 (abstract).

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Possible endocannabinoid control of colorectal cancer growth

Ligresti, Alessia, et al.

Gastroenterology. 2003 Sep, 125(3): 677-687 (abstract).

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Delta-9-Tetrahydrocannabinol as an Antiemetic for Patients Receiving Cancer Chemotherapy: A Comparison with Prochlorperazine and a Placebo

Frytak, Stephen et al.

Annals of Internal Medicine. 1979 Dec 1, 91(6): 825-830 (abstract).