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Colon & Colorectal Cancer

US Patent Application 20130059018 A1, Mar 7, 2013 - Phytocannabinoids in the treatment of cancer

Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer

Aviello, Gabriella, et al.

Journal of Molecular Medicine. 2012 Aug, 90(8): 925-934 (abstract).

Induction of Apoptosis by Cannabinoids in Prostate and Colon Cancer Cells Is Phosphatase Dependent

Sreevalsan, Sandeep, et al.

Anticancer Research. 2011, 31: 3799-3808 (Full).

High Tumour Cannabinoid CB1 Receptor Immunoreactivity Negatively Impacts Disease-Specific Survival in State II Microsatellite Stable Colorectal Cancer

Gustafsson, Sofia B, et al.

PLOS ONE. 2011 Aug 25, e0023003 (Full online article).

Concerted Action of CB1 Cannabinoid Receptor and Deleted in Colorectal Cancer in Axon Guidance

Argaw, Anteneh, et al.

The Journal of Neuroscience. 2011 Jan 26, 31(4): 1489-1499 (Full).

Effects of Anandamide on Polyamine Levels and Cell Growth in Human Colon Cancer Cells

Linsalata, Michele, et al.

Anticancer Research. 2010, 30: 2583-2590 (Full).

Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependant NSAID-activated gene-1 in colon cancer cells

Thapa, Dinesh, et al.

Biochemical Pharmacology. 2010 Jul 1, 80(1): 62-71 (abstract).

The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells

Greenhough, Pastos, et al.

International Journal of Oncology. 2010 Jul, 37(1): 187-193 (abstract).

Rimonobant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon

Santoro, Antonietta, et al.
International Journal of Cancer. 2009, 125: 996-1003 (Full).

Cannabinoid Receptor Activation Induces Apoptosis through Tumor Necrosis Factor α-Mediated Ceramide De Novo Synthesis in Colon Cancer Cells

Cianchi, Fabio, et al.

Clinical Cancer Research. 2008, 14: 7691-7700 (Full).

Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines

Notarnicola, Maria, et al.

Scandinavian Journal of Gastroenterology. 2008, 43(1): 66-72 (abstract).

The cannabinoid Δ9-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells

Greenhough, Alexander, et al.

International Journal of Cancer. 2007, 121: 2172-2180 (Full).

A Cannabinoid Anticancer Quinon, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo Study

Kogan, Natalya M, et al.

The Journal of Pharmacology and Experimental Therapeutics. 2007, 322(2): 646-653 (Full)

The cannabinoid CB2 receptor: a good friend in the gut

Izzo, AA, et al.

Neurogastroenterology & Motility. 2007, 19: 704-708 (Full).

Involvement of cannabinoid receptors in inflammatory hypersensitivity to colonic distension in rats

Sanson, M, et al.

Neurogastroenterology & Motility. 2006, 18: 949-956 (Full).

Cannabinoids and cancer: potential for colorectal cancer therapy

Patsos, HA, et al.

Biochemical Society Transactions. 2005, 33(4): 712-714 (Full).

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2

Pastos, HA, et al.

GUT. 2005, 54: 1741-1750 (Full).

Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing

Wright, Karen, et al.

Gastroenterology. 2005 Aug, 129(2): 437-453 (abstract).

Possible endocannabinoid control of colorectal cancer growth

Ligresti, Alessia, et al.

Gastroenterology. 2003 Sep, 125(3): 677-687 (abstract).

Delta-9-Tetrahydrocannabinol as an Antiemetic for Patients Receiving Cancer Chemotherapy: A Comparison with Prochlorperazine and a Placebo

Frytak, Stephen et al.

Annals of Internal Medicine. 1979 Dec 1, 91(6): 825-830 (abstract).

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