Cannabis Learning EDU
Insomnia
Statistics on Insomnia:
50-70 million US adults have a sleep disorder. Insomnia is the most common specific sleep disorder, with short term issues reported by about 30% of adults and chronic insomnia by 10%.
37% of 20-39 year-olds report short sleep duration.
40% of 40-59 year-olds report short sleep duration.
Drowsy driving is responsible for 1,550 fatalities and 40,000 nonfatal injuries annually in the United States.
100,000 deaths occur each year in US hospitals due to medical errors and sleep deprivation has been shown to make a significant contribution.
(Source: American Sleep Association, www.sleepassociation.org/sleep/sleep-statistics/)
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Tringale, Rolando, et al.
O’Shaughnessy’s. 2011 Apr, 31-32.
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Murillo-Rodriguez, Eric, et al.
Sleep. 2003 Aug, 26(8): 943-947.
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Grotenhermen, Franjo.
Neuroendocrinology Letters. 2004 Apr, 1-2: 15-23.
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Russo, Ethan B., et al.
Chemistry & Biodiversity. 2007 Aug 21, 4(8): 1729-1743 (abstract).
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Cannabidiol, a constituent of Cannabis Sativa, modulates sleep in rats
Murillo-Rodriguez, Eric, et al.
FEBS Letters. 2006 Aug 7, 581(18): 4337-4345.
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The modulatory role of endocannabinoids and sleep
Murillo-Rodriguez, Eric.
Revisita de Neurologia. 2008, 46(3): 160-166 (abstract).
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The role of the CB1 receptor in the regulation of sleep
Murillo-Rodriguez, Eric.
Progress in Neuro-Psycopharmacology and Biological Psychiatry. 2008 Aug 1, 32(6): 1420-1427 (abstract).
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Nicholson, Anthony N., et al.
Journal of Clinical Psychopharmacology. 2004 Jun, 24(3): 305-313 (abstract).
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Established and potential therapeutic applications of cannabinoids in oncology
Walsh, Declan, et al.
Supportive Care in Cancer. 2003 Mar, 11(3): 137-143 (abstract).
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Functional role for cannabinoids in respiratory stability during sleep.
Carley, DW, et al.
Sleep. 2002, 25(4): 391-398 (abstract).